Mediplorer CO₂ Skincare — Japanese Carboxytherapy Science

The Art and Science of Oxygen Renewal

Mediplorer is a Japanese dermatological brand founded in 1997 by Dr. Masato Hiki, a dermatologist and the inventor of the world’s first professional CO₂ gel mask.
From its origin in clinical research, Mediplorer has evolved into one of Japan’s most respected skincare lines — where medical precision meets the quiet elegance of Japanese formulation.

Unlike standard carboxytherapy products that simply bubble on the skin, Mediplorer CO₂ Skincare uses a patented two-phase activation system. When the gel and powder interact, they generate a controlled CO₂ release directly on the skin surface — creating a safe, needle-free version of carboxytherapy that stimulates circulation, oxygen delivery, and visible rejuvenation.

Why Mediplorer Is Different

Every Mediplorer formula is built around the principle that oxygen is the foundation of renewal. The process is rooted in the Bohr effect — a natural physiological mechanism where an increase in CO₂ prompts red blood cells to release oxygen into tissues.
This gentle oxygen exchange awakens cellular activity, improves microcirculation, and supports collagen regeneration — all without irritation or downtime.

Clinical studies published in Skin Research and Technology (2022) and The Journal of Cosmetic Dermatology (2023) confirm that topical CO₂ therapy can measurably increase local oxygen levels, improve skin firmness, and reduce fine lines after a consistent course.

The Vitamin C System — Antioxidant Intelligence

What makes Mediplorer unique is its use of a multi-molecular Vitamin C complex that remains active during the CO₂ reaction:

• Pure Ascorbic Acid delivers brightening and anti-aging effects.

• Sodium Ascorbyl Phosphate (SAP) acts as a stable, water-soluble form that supports clarity and antioxidant defense.

• Trisodium Ascorbyl Palmitate Phosphate (APPS) penetrates deeper layers, activating collagen synthesis and improving tone.

This synergy enhances elasticity, combats oxidative stress, and reinforces the barrier — a hallmark of Mediplorer’s clinical precision.

Advanced Actives for Visible Results

Each mask and gel is enriched with carefully balanced bio-actives:

• Resveratrol to protect against environmental aging;

• Fucoidan and Hyaluronic Acid for deep hydration;

• Ceramide complexes to restore barrier strength;

• Acetyl Hydroxyproline to reinforce the collagen network.

Together, they create skin that feels smoother, firmer, and more resilient after every use.

For Whom

Mediplorer CO₂ Skincare is ideal for:

• skin showing signs of fatigue, dullness, or loss of firmness;

• fine lines, enlarged pores, uneven tone, or post-treatment recovery;

• both men and women seeking high-performance, anti-age results without irritation.

For sensitive or reactive skin, the standard CO₂ Gel Mask offers a gentle introduction, while the Premium formula — with 40 % more active CO₂ and peptides — is reserved for experienced users or professional guidance.

At-Home Ritual

Apply the CO₂ gel and powder evenly to the face, neck, and décolleté for 15–20 minutes.
During activation, a light warmth and tingling may occur — a sign that oxygen exchange is underway.
Remove gently, then follow with a hydrating essence or light moisturizer to seal in radiance.
Used two to three times per week, the skin appears brighter, smoother, and visibly renewed.

Professional Insight

Mediplorer CO₂ Skincare is trusted by dermatologists and aesthetic clinics across Japan and Europe.
At Timeless Beauty Amsterdam, these formulas are part of our advanced in-clinic treatments and available for at-home maintenance — allowing you to preserve the same professional glow between visits.

A Closing Note — From Timeless Beauty Amsterdam

True anti-aging begins where oxygen meets calm.
Mediplorer is more than skincare — it is a quiet dialogue between science and vitality, between what is seen and what is felt.
Every application is a reminder that beauty, like oxygen, is a form of life itself.